Eric Topol

physician-scientist, author, editor

Public Key

npub12pmlfp4r7tmj6plqal2ukq92ysmnguunyum3ahvj6hrr57malefsmmjy4r

NIP-05 Address

erictopol_at_mstdn.social@mostr.pub

Profile Code

nprofile1qqs9qal5s63l9aedqlswl4wtqz4zgde5wwfjwdc7mkfdt3360d7lu5cpz4mhxue69uhhyetvv9ujumt0wd68ytnsw43qh6x8z0

Publishing to

relay.mostr.pub

Author Public Key

npub12pmlfp4r7tmj6plqal2ukq92ysmnguunyum3ahvj6hrr57malefsmmjy4r

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Last Notes

2024-08-03 15:47:47

Characterizing the significance and response to the current US Covid wave
A new Ground Truths analysis https://erictopol.substack.com/p/the-indomitable-covid-virus
https://media.mstdn.social/media_attachments/files/112/898/871/412/386/636/original/3ae81cad964f027e.png

2024-07-24 22:56:08

Masks work. Again. New Randomized trial
https://www.bmj.com/content/386/bmj-2023-078918
https://media.mstdn.social/media_attachments/files/112/843/932/605/534/991/original/a20fae714a3d7b41.jpg

2024-07-19 15:52:37

The rise of the KP.3.1.1 variant, which along with KP.3, accounts for most of Covid cases in the US summer wave now
It has a decided growth advantage, with higher infectivity and immune evasion compared with prior SARS-CoV-2 variants
https://media.mstdn.social/media_attachments/files/112/813/955/799/337/904/original/8fc689e2a6249889.png

2024-07-14 14:20:09

- reply

@npub1lgy…aefg thank you!

2024-06-20 14:44:27

Vaccination prevents loss of brain hippocampus neurogenesis, loss of memory, accumulation of IL-1β, #LongCovid central nervous system hit in the mouse model
https://nature.com/articles/s41590-024-01868-z

2024-04-27 18:00:47

Here's what we know about the KP.2 FLiRT variant that is destined to become the new dominant variant here (now 1 of 4new Covid cases)
http://biorxiv.org/cgi/content/short/2024.04.24.590786
>3-fold resistance to current booster (XBB.1.5)
https://media.mstdn.social/media_attachments/files/112/344/486/716/259/322/original/d319b0a39a2ea98b.png

2024-03-12 20:48:00

Beyond ~30 million excess deaths, "The COVID-19 pandemic caused the most severe drops in life expectancy seen in 50+ years."
https://healthdata.org/research-analysis/library/mortality-life-expectancy-and-population
https://thelancet.com/journals/lancet/article/PIIS0140-6736(24)00476-8/fulltext
https://media.mstdn.social/media_attachments/files/112/084/678/912/017/275/original/1c207779300f5951.jpeg

2024-03-01 20:54:26

My thoughts on the CDC new 5-day no isolation policy
https://www.cnn.com/2024/03/01/health/cdc-covid-isolation-recommendations?cid=ios_app
https://media.mstdn.social/media_attachments/files/112/022/419/095/593/136/original/2840961fd2b6cd88.png

2023-10-03 18:56:45

Had a scheduled appointment today a CCS pharmacy for a Covid vaccine booster. When I checked in, I’m told they ran out and they have “supply issues.” No prior notification, despite their having my email and text info. Pathetic roll out and CVS execution

2023-09-20 00:16:01

On the new Covid boosters:
Since @CDCgov gave them full approval, by law health insurers have to provide them for free. So don't let your insurer get away with any charge to you!

2023-09-12 22:09:40

Here it is
https://media.mstdn.social/media_attachments/files/111/054/459/437/332/323/original/3f628c09a4815b93.png

2023-08-21 15:11:34

There are 2 new publications today on Covid follow-up at 2 years that shed light on #LongCovid, but there are still many known unknowns, reviewed here
https://erictopol.substack.com/p/long-term-long-covid
https://media.mstdn.social/media_attachments/files/110/928/244/355/574/542/original/94d26b0c7f20f4d1.png

2023-08-20 14:42:26

A telling graph
US life expectancy by state vs countries https://www.nytimes.com/2023/08/16/opinion/health-care-life-expectancy-poverty.html?searchResultPosition=1
https://media.mstdn.social/media_attachments/files/110/922/467/845/734/111/original/9969bf50830e5fcc.png

2023-08-18 19:01:57

Just published
When a nasal vaccine provides superior immune response compared with a shot (2 doses of each). Results from a randomized clinical trial, including vs Omicron, and with less local and systemic adverse effects
https://nature.com/articles/s41541-023-00717-8
https://media.mstdn.social/media_attachments/files/110/912/163/729/947/135/original/ab1e4d20b974c6f3.png

2023-08-16 22:57:34

Among over 4.2 million people, Covid was associated with a significant increased risk of developing multiple types of autoimmune diseases compared with uninfected, and vaccination provided protection
https://thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00331-0/fulltext
https://media.mstdn.social/media_attachments/files/110/901/765/597/030/557/original/713accda3618f0ee.png

2023-08-15 15:38:30

On the 52 American doctors (Hall of Shame) who propagated Covid misinformation throughout the pandemic regarding vaccines, masks, promoting treatments without evidence, and conspiracy theories
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808358
https://media.mstdn.social/media_attachments/files/110/894/374/985/636/105/original/6707e04595af51ca.png

2023-08-08 21:46:24

It's been almost 60 years since the Epstein-Barr virus (EBV) was discovered, now with strong links to multiple sclerosis other autoimmune conditions, but no vaccine. A step in the right direction today
https://nature.com/articles/s41467-023-39770-1
https://media.mstdn.social/media_attachments/files/110/856/187/434/138/428/original/a924c61ed7c32982.png

2023-08-08 16:18:44

We haven’t yet seen the actual data but a 20% reduction of cardiovascular events in a 17, 500 participant randomized trial of a GLP-1 anti-obesity drug is a big deal and likely will change the reimbursement landscape (and further promote uptake)
https://media.mstdn.social/media_attachments/files/110/854/898/207/984/799/original/8ff691daaffdf4f0.webp
https://media.mstdn.social/media_attachments/files/110/854/898/989/650/033/original/7e2452fd8c904b74.png

2023-08-08 15:29:50

Truth.
https://media.mstdn.social/media_attachments/files/110/854/706/824/417/289/original/64bce6e4dbebbf18.png

2023-08-07 23:03:04

In the largest study to measure cytokines and chemokines during Covid, with or without vaccination, a lower inflammatory profile was seen with prior vaccination, supporting its potential short and long- term protective benefit
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00171-4/fulltext
https://media.mstdn.social/media_attachments/files/110/850/824/844/548/301/original/24c0cbd283f70ceb.png

2023-08-07 14:24:38

A visit to the doctor in 2023 :-(
https://media.mstdn.social/media_attachments/files/110/848/787/939/169/581/original/69f4013437ba11d7.jpeg