What is causing Metabolic Syndrome & Obesity?
Mitochondrial Dysfunction → Leptin Resistance → Fat Storage
This leads to two pathways:
1. Low Personal Fat Threshold → Cannot store more fat → Insulin Resistance → Metabolic Syndrome
2. High Personal Fat Threshold → Can store more fat → Insulin Sensitive → Obesity (Then eventually Metabolic Syndrome)
chrispatrick / Chris Patrick
npub124…30zsu
2025-02-16 02:22:02
Author Public Key
npub124uatsq6pv74trzwvt34y4sx2z0uflhse7tkrv0pl69e8kcsfhkse30zsuPublished at
2025-02-16 02:22:02Event JSON
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"content": "What is causing Metabolic Syndrome \u0026 Obesity?\n\nMitochondrial Dysfunction → Leptin Resistance → Fat Storage\n\nThis leads to two pathways:\n\n1. Low Personal Fat Threshold → Cannot store more fat → Insulin Resistance → Metabolic Syndrome\n\n2. High Personal Fat Threshold → Can store more fat → Insulin Sensitive → Obesity (Then eventually Metabolic Syndrome)",
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