"I was like, 'How am I going to give this story to a young Max?' […] That's when I came up with the idea well, I can distill this down into two protocols: the leptin prescription and cold thermogenesis. […]
"So the leptin prescription basically is, you must stimulate POMC, everywhere in your body that it's located, via UV light. So that means the sun is important.
"[…] everybody in Australia that tells you the sun is bad, […] they need to understand that beta endorphin is also made in POMC. What is beta endorphin? It is an opioid chemical. Nature made us to be addicted to the sun. Hard stop.
"Everybody in Australia is going, 'You got to be shitting me. We're slipping, slathering, sunglassing and all this stuff.' You are doing everything possible to ruin POMC signaling in you by doing that. […]
"Then you make another opioid, it's called metencephalon, also from this. […] It's highly important in neuroimmune modulation and also immune modulation.
"Well everybody knows (correct me if I'm wrong) four percent of the world now suffers from autoimmune conditions. And Max, I'm sure you can tell your own audience that when you're in medical school and they teach you about MS, they never have an answer for what causes it. The only thing they know is that when you get closer to the equator it goes away. Right?
"So your job as a doctor is to treat all these people with this condition and try to figure out how in the hell it happens. And you come up with all these big pharma solutions that are worth nothing. It's garbage. Hard garbage.
"What they need is the sun. Why?
"Because everybody that has MS has a defect in POMC. They don't have enough of it. And that's where you begin.
"So that's the functional idea behind the leptin prescription: is get mammals, who absolutely can't live without the sun, back into the sun. That was goal number one of decentralized Jack." —Dr. Jack Kruse with Max Gulhane MD @ 39:56–43:45 https://youtu.be/Ln3WszTq0uA&t=2396