Event JSON
{
"id": "6718de64bcf8b6392047238fb7301d2b867ccc84732eabc0f56cc94eca840588",
"pubkey": "3e45c31cdfbf1f386c345672cbc9f1be2abe7931c240e997d0f909a0d14244c8",
"created_at": 1721287539,
"kind": 1,
"tags": [
[
"t",
"cas12a"
],
[
"t",
"AAV"
],
[
"t",
"genetherapy"
],
[
"t",
"plosbiology"
],
[
"t",
"GenomeEditing"
],
[
"proxy",
"https://fediscience.org/users/PLOSBiology/statuses/112806300194246931",
"activitypub"
]
],
"content": "Existing #Cas12a nucleases are too large for #AAV-based #GeneTherapy. @grimmlab explores a #PLOSBiology study of a new Cas12a variant, compatible with in vivo #GenomeEditing via all-in-one AAV delivery. Paper: https://plos.io/3UWqpjC Primer: https://plos.io/4fmjk5F\n\nhttps://fediscience.org/system/media_attachments/files/112/806/300/075/509/040/original/a87091cef67947cc.jpg",
"sig": "5b52bdf15f1f8f2e3437dad72f45bdd6c23c54eb86d8c3645c759b425d9a2e6404f6840583f17f0f15cf7686f7ab887839dc795b8a7368f00863afe432cd76e8"
}
