npub1u2vwrtzycscs56pxwmq7llk0p6s07egpxg58cvc7qgu3vr0vhszsf54999 (npub1u2v…4999)
The emerging story for nearly all brain disorders is that the same symptoms follow from a plethora of causes and different individuals with the ‘same’ disorder will require different treatments (precision medicine). I believe that the degeneracy you are talking about here is closely related.
Cystic fibrosis (while not a brain disorder) is one example - it’s always a mutation to one gene, but the drug needed to treat it depends on what the mutation is. Now take that complexity and multiply it for the more typical disorders that aren’t associated with a single gene (but many genes + environmental interactions).
So yes on appreciating the degeneracy and understanding those many biophysical stuffs to one function principles!
Nicole Rust /
npub1cu…0zuw2
2023-09-07 10:36:27
in reply to nevent1q…jkqv
Author Public Key
npub1cud99prgj4etl597aaxthxenrcjmfxl92dgj8snf9a9p8ctupfyq80zuw2Published at
2023-09-07 10:36:27Event JSON
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"content": "nostr:npub1u2vwrtzycscs56pxwmq7llk0p6s07egpxg58cvc7qgu3vr0vhszsf54999 \nThe emerging story for nearly all brain disorders is that the same symptoms follow from a plethora of causes and different individuals with the ‘same’ disorder will require different treatments (precision medicine). I believe that the degeneracy you are talking about here is closely related. \n\nCystic fibrosis (while not a brain disorder) is one example - it’s always a mutation to one gene, but the drug needed to treat it depends on what the mutation is. Now take that complexity and multiply it for the more typical disorders that aren’t associated with a single gene (but many genes + environmental interactions).\n\nSo yes on appreciating the degeneracy and understanding those many biophysical stuffs to one function principles!",
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