PLOS Biology on Nostr: #Bemnifosbuvir (AT-527) & AT-752 are #antiviral guanosine analogues currently in ...
#Bemnifosbuvir (AT-527) & AT-752 are #antiviral guanosine analogues currently in clinical trials. This study reconstitutes their intracellular 5-step enzymatic activation pathway, characterizing each #enzyme complex at atomic resolution #PLOSBiology
https://plos.io/3WVSAjG 
Published at
2024-08-28 08:08:39Event JSON
{
"id": "6410eb0a8c02174ba28d178e9c4b4f328ecf199d1b3fa088d6033f50ce7af583",
"pubkey": "3e45c31cdfbf1f386c345672cbc9f1be2abe7931c240e997d0f909a0d14244c8",
"created_at": 1724832519,
"kind": 1,
"tags": [
[
"t",
"bemnifosbuvir"
],
[
"t",
"antiviral"
],
[
"t",
"enzyme"
],
[
"t",
"plosbiology"
],
[
"proxy",
"https://fediscience.org/users/PLOSBiology/statuses/113038623983887534",
"activitypub"
]
],
"content": "#Bemnifosbuvir (AT-527) \u0026 AT-752 are #antiviral guanosine analogues currently in clinical trials. This study reconstitutes their intracellular 5-step enzymatic activation pathway, characterizing each #enzyme complex at atomic resolution #PLOSBiology https://plos.io/3WVSAjG\n\nhttps://fediscience.org/system/media_attachments/files/113/038/623/827/006/048/original/d11f0e45e3a9bfb9.jpg",
"sig": "b5c9e602710705b18347695e9dbdf914016a0ef7f991815754930afacf9826e8f41f1d4e34c514ba28e3b091a589989c55a4437080b292dbe1d02c2f907aff75"
}
