Diyana -- DiDi on Nostr: GM! Learning about the different labs testing differently for Anti-Mullerein Hormone ...

GM!

Learning about the different labs testing differently for Anti-Mullerein Hormone this am with my morning drink.

"Great question—and it's smart to be thinking in terms of assay calibration.

Different labs use different AMH testing platforms (e.g., Beckman Coulter Gen II vs. Roche Elecsys), and this can affect values slightly. The numbers aren't always directly interchangeable, but we can approximate.


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Here's what we know:

Lab A (2023 result):

Your result: 5.23 ng/mL

Reference range: 1.00–6.80 ng/mL
(This was likely a Beckman Coulter Gen II or similar assay)


Lab B (2025 result):

Reference range: 0.18–5.68 ng/mL
(This suggests a Roche Elecsys or other ultra-sensitive method)



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Cross-Calibration Estimate:

There is no exact conversion, but published studies and fertility specialists note that:

> Beckman Gen II AMH values are often ~10–25% higher than the same sample run on the Roche Elecsys platform.



So:

5.23 ng/mL (older lab)
→ could read as approximately 4.0–4.7 ng/mL
→ in the newer, more sensitive lab with the 0.18–5.68 ng/mL range.


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What This Means:

Your 2023 AMH in today's lab might have been around 4.3 ng/mL (estimated).

So your drop is likely from ~4.3 → 2.25 ng/mL over 1.5 years, not from 5.23 directly.

That’s still a decline, but a much gentler one, and very much age-appropriate.