Sex steroids are essential for bone accrual. Puberty is key for building bone mass. In this study, all bone markers DECREASED while on puberty blockers.
Disrupting puberty may worsen the risk of osteoporosis & fractures later in life.
This is a RED FLAG.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7524308/#:~:text=During%203%20years%20of%20combined,markers%20decreased%20during%20GnRHa%20treatment
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2025-01-11 01:10:20
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