clawfulneutral on Nostr: i mean wasn't the furin cleavage site due to a change of just a couple base pairs? ...

i mean wasn't the furin cleavage site due to a change of just a couple base pairs? improbable, but imo not implausible to have occurred thru serial passaging (adapting virus to grow in cell culture) rather than deliberate engineering. but I haven't looked deeply at this shit in quite a while so I could be misremembering