This "Journal Club" article on the #EvoDevo #hourglass pattern is a bit surprising
https://www.nature.com/articles/s41576-024-00717-x
Yes Domazet-Lošo & Tautz 2010 was instrumental in putting the question on the forefront of the field, but (1) it was together with Kalinka et al 2010 (https://doi.org/10.1038/nature09634), (2) the Domazet-Lošo & Tautz paper bioinformatics was weird, with notably use of raw expression measures rather than log-transformed expression, and the results were not suported by proper analysis.
Marc Robinson-Rechavi /
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2024-06-24 15:52:08
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